Research
The Section of Colon and Rectal
Surgery has a strong commitment to medical and scientific research with ongoing
collaborative projects that focus on state-of-the art research related to
colorectal surgery.
Active research studies include:
- Treatment of fistula in ano using a porcine intestine submucosa graft
(Surgisis® AFP) Cook plug.
- Study of medications for the treatment of postoperative ileus in patients
undergoing laparotomy for large bowel resection.
- Several molecular studies to help determine patients at high risk for
cancer recurrence.
- Ex-vivo sentinel lymph node mapping in patients undergoing laparoscopic
colectomy for colon cancer.
- Ex-vivo sentinel lymph node mapping in patients undergoing proctectomy
for rectal cancer.
- A Phase II study of surgical debulking and biweekly intraperitoneal chemotherapy
in patients with pseudomyxoma peritonei or peritoneal carcinomatosis.
- Timing of rectal cancer response to chemoradiation.
- Crohn’s tissue bank and database.
- Hereditary colon and rectal database.
The section also engages in collaborative
projects on the genetics of colorectal cancer and its therapies and the CREATE
(Comprehensive Research on Expressed Alleles in Therapeutic Evaluation) Pharmacogenetics
Research Network at Washington University School of Medicine. More information
can be obtained at: http://dsgweb.wustl.edu/PROJECTS/MP15.html.
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Washington University physicians are the medical staff of Barnes-Jewish Hospital and St. Louis Children's Hospital
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